Hematologic Malignancies

n Hematologic Malignancies: Methods and Techniques, a panel of acknowledged experts review many of the key molecular methods used for the diagnosis and subsequent management of hematologic malignancies. These clinically relevant techniques range from routine test procedures to highly sophisticated methods currently offered only by specialized reference laboratories, and fall into five major groups: cytogenetics, polymerase chain reaction, flow cytometry, cytochemistry and immunochemistry, and apoptosis and cytokine receptors. Serving both clinical and experimental needs, Hematologic Malignancies: Methods and Techniques provides an array of powerful tools that will guide clinicians— especially hematologists, oncologists, and pathologists— to better diagnose and manage their patients with hematologic malignancies, and enable researchers to assess the anticancer effect of agents that impact cancer cells at the molecular level.

1. Cytogenetics Analysis
Avery Sandberg; Zhong Chen
pp. 3-18

2. FISH Analysis
Avery Sandberg; Zhong Chen
pp. 19-42

3. Comparative Genomic Hybridization for the Analysis of Leukemias and Lymphomas
Michael Baudis; Martin Bentz
pp. 43-64

4. Spectral Karyotyping (SKY) of Hematologic Malignancies
Eva Hilgenfeld; Hesed Padilla-Nash; Oskar Haas; Hubert Serve; Evelin Schröck; Thomas Ried
pp. 65-79

5. Molecular Genetic Methods in Diagnosis and Treatment
Pamela Ward; Alan Kinniburgh
pp. 83-116

6. Detecting Monoclonal Immunoglobulin and T-Cell Receptor Gene Rearrangements in B- and T-Cell Malignancies by Polymerase Chain Reaction
Pamela Sykes
pp. 117-132

7. Quantifying Residual Leukemia by "Clone-Specific" Polymerase Chain Reaction
Michael Brisco
pp. 133-156

8. NPM-ALK Reverse Transcriptase- Polymerase Chain Reaction for Detecting the t(2;5) of Non-Hodgkin' s Lymphoma
Sheila Shurtleff; James Downing; Stephan Morris
pp. 157-176

9. Diagnostic Flow Cytometry in Hematologic Malignancies
Gerald Marti; Maryalice Stetler-Stevenson; Thomas Fleisher
pp. 179-215

10. Flow Cytometric Analysis of Hematologic Neoplasia
Raul Braylan; John Anderson
pp. 217-230

http://rapidshare.de/files/34023312/055-Hematologic_Malignancies.pdf